RecruitingACTRN12614000182695

Critical Evaluation of a Targeted Point of Care (POC) ROTEM (Registered Trademark) and Multiplate (Registered Trademark) Guided Coagulation and Haemostasis Management Programme in Cardiac Surgical Patients

Sponsor

Gold Coast University Hospital Critical Care Research Group

Enrollment

200 participants

Start Date

Jun 29, 2015

Study Type

Observational

Conditions

Coagulation and transfusion management in patients undergoing cardiac surgery

Summary

There is an increasing body of evidence that the adoption of point of care (POC) guided coagulation and haemostatic management algorithms in the cardiac surgical patient population results in improved outcomes. We aim to critically evaluate our POC programme at the Gold Coast University Hospital (GCUH). In addition, we aim to evaluate the prognostic importance of baseline and perioperative humeral factors relating to haem catabolism (bilirubin/carboxy haemoglobin) in modulating haemostatic function and predicting post-operative outcomes in patients undergoing cardiac surgery

Eligibility

Sex: Both males and femalesMin Age: 18 YearssMax Age: 100 Yearss

Plain Language Summary

Simplified for easier understanding

This study is looking at how a special real-time blood clotting test system (called point-of-care testing) is being used to guide care for patients having heart surgery at Gold Coast University Hospital. Researchers want to understand whether using this guided approach leads to better outcomes and fewer bleeding problems after surgery. They are also studying certain blood markers to see if they predict how well patients recover. You may be eligible if: - You are 18 years of age or older - You are scheduled to undergo heart (cardiac) surgery You may NOT be eligible if: - You are under 18 years of age Talk to your doctor about whether this trial might be right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

ROTEM / Multiplate coagulation assessment and product transfusion protocol. At 4 predefined time points a ROTEM/Multiplate panel of tests will be analysed: 1. Pre-operatively 2. 30 mins before comi

ROTEM / Multiplate coagulation assessment and product transfusion protocol. At 4 predefined time points a ROTEM/Multiplate panel of tests will be analysed: 1. Pre-operatively 2. 30 mins before coming off Cardiopulmonary Bypass 3. 10 mins after coming off CPB and after Protamine 4. On admission to ICU post-operatively At each of these time points blood product replacement will be guided by the results. There is a predefined and validated algorithm. In addition further tests will be done 10 minutes after any haemostatic intervention. Further testing can be done at clinician discretion - i.e. In the presence of on-going bleeding further testing will be performed. Testing will cease once there is no further evidence of on-going bleeding .

Locations(1)

Gold Coast Hospital - Southport

QLD, Australia

View Full Details on ANZCTR

For the most up-to-date information, visit the official listing.

Visit

ACTRN12614000182695