RecruitingPhase 4ACTRN12614000262606

Ultrasound guided Transversus Abdominis Plane block: An evaluation of its efficacy in reducing post-op opioid requirements in Caesarean section

Parturients undergoing elective Caesarean section, Transversus Abdominis Plane block compared to intravenous Morphine via Patient Controlled Analgesia PCA to achieve better Postoperative pain control.

Sponsor

Shahid Adeel

Enrollment

60 participants

Start Date

Jun 22, 2013

Study Type

Interventional

Conditions

Pain management after Caesarean section

Summary

The transversus abdominis plane (TAP) block is a new regional anaesthesia technique that provides analgesia to the peritoneum, skin as well as the muscles of the anterior abdominal wall. It is easy to perform with a high margin of safety, especially under ultrasound guidance. TAP blocks have been described as an effective component of multimodal postoperative analgesia for a wide variety of abdominal procedures including caesarean section. Current reports demonstrated its safety and efficacy in reducing opioids consumption. Post-op analgesia in patient undergoing emergency caesarean section has conventionally been a multi-modal analgesia comprising of morphine PCA, regular paracetamol and NSAIDs. These have resulted in large consumption of morphine which is excreted via breast milk. These also result in higher sedation score and higher incidence of post operative nausea and vomiting

Eligibility

Sex: FemalesMin Age: 18 Yearss

Plain Language Summary

Simplified for easier understanding

This study is testing whether adding a nerve block technique called a TAP (Transversus Abdominis Plane) block to routine pain management after a planned caesarean section reduces the need for strong pain medicines (opioids) like morphine after surgery. Less opioid use is important because morphine passes into breast milk and can cause side effects like nausea and drowsiness. You may be eligible if: - You are 18 years of age or older - You are scheduled for an elective (planned, not emergency) caesarean section - You are rated as ASA class 1 or 2 (generally healthy or mild health conditions) - You will be having spinal anaesthesia for the operation You may NOT be eligible if: - You are having an emergency caesarean section - You are rated as ASA class 3 or 4 (significant health conditions) - You are morbidly obese - You have an allergy to local anaesthetic medicines Talk to your doctor about whether this trial might be right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Arm 1 patients will receive TAP block, 0.25% Bupivacaine 20 ml bilaterally along with PCA Morphine Arm 2 patients will receive TAP block, 0.166% bupivacaine 30 ml bilaterally along with PCA Morph

Arm 1 patients will receive TAP block, 0.25% Bupivacaine 20 ml bilaterally along with PCA Morphine Arm 2 patients will receive TAP block, 0.166% bupivacaine 30 ml bilaterally along with PCA Morphine TAP block is administered immediatly post caesarean section after skin suturing. PCA Morphine is made available in immediate post operative period in recovery room. PCA 1mg morphine per dose. lockout interval of 5 minutes. no background infusion and Maximum of 30 mg morphine per 4 hours.

Locations(1)

Bahrain

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ACTRN12614000262606