RecruitingACTRN12614000517673

Effect of progressive resistance training in women with polycystic ovary syndrome. A feasibility study

A randomised control trial comparing the benefits of progressive resistance training and/or usual care on health status in women with polycystic ovary syndrome


Sponsor

Miss Lisa Vizza

Enrollment

40 participants

Start Date

Apr 1, 2014

Study Type

Interventional

Conditions

Summary

The purpose of this study is to investigate the feasibility of a 12 week progressive resistance training program versus usual care in overweight women with polycystic ovary syndrome. Participants will be required to attend two baseline and two follow up session for 1-2 hours at the University of Western Sydney Campbelltown for the assessment of body composition, isometric strength, menstrual cycle and psychological status. On separate days participants will also be asked to undertake fasting blood samples first thing in the morning at Douglas Hanly Moir pathology. Upon completion of baseline testing participants will be randomised to either the PRT or usual care group and will be given to participants in a sealed envelope. Participants randomised to the PRT group will be required to exercise four sessions per week, where two sessions will be supervised at the University Western Sydney Campbelltown campus while the other two sessions will be unsupervised (i.e. home based). . If you are allocated to the usual care group, you will be required to continue with your usual care management for the duration of the trial. The researcher will contact you weekly to document for any adverse events or reactions. Participants will also be required to maintain a diary to record their menstrual cycle details such as cycle length (i.e. day one of period and day one of next period), signs and symptoms etc.


Eligibility

Sex: FemalesMin Age: 18 YearssMax Age: 42 Yearss

Plain Language Summary

Simplified for easier understanding

This study is looking at whether a 12-week weight training (progressive resistance training) program is possible and helpful for overweight women who have polycystic ovary syndrome (PCOS). PCOS is a hormonal condition that can cause irregular periods, excess body hair, and difficulty getting pregnant. Participants will be assigned to either the exercise program (with two supervised and two home sessions per week) or usual care, and will have their body composition, strength, menstrual cycle, and mental health checked before and after the program. You may be eligible if: - You are a woman between 18 and 42 years old - You have been diagnosed with PCOS using the Rotterdam Criteria - Your BMI is greater than 25 kg/m² - You are not currently on fertility treatments - You are not already doing a heavy resistance training program You may NOT be eligible if: - You are pregnant or breastfeeding - You have a history of heart, liver, kidney, or respiratory disease - You have uncontrolled high blood pressure or cancer - You have smoked cigarettes in the last 6 months - You have any medical condition that makes exercise unsafe or impossible to assess Talk to your doctor about whether this trial might be right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Women will be randomised into either the progressive resistance training group or usual care group. The trial will run for 12 weeks. Both groups will need to attend two baseline and two follow up sess

Women will be randomised into either the progressive resistance training group or usual care group. The trial will run for 12 weeks. Both groups will need to attend two baseline and two follow up session for 1-2 hours. Both groups will be assessed weekly to document for adverse changes or events Exercise intervention PRT- Participants randomised to the progressive resistance training (PRT) will be required to undertake every week for 12 weeks: two supervised exercise sessions on non consecutive days for 1 hour at the University of Western Sydney Campbelltown or Penrith campus as well as perform two unsupervised sessions for 30 minutes at home. The exercises will consist of muscles involving the arms, back, legs and core. the basis of the intervention is to train to neuromuscular fatigue (for instance training at an RM of 8-12 repetitions. for the supervised sessions, exercises will consist of mainly machines and free weight activities. for the first two weeks each exercise will be performed at 2 sets of 8-12 RM. on the third week most exercises will be progressed to 3 sets of 8-12 RM until study completion. Exercise sessions will be progressed and adjusted to account for individuals exercise capacity and training adaptations. The home based exercises will consist of six different body callisthenics (such as body weight exercises) without the use of machines/free weights and each exercise will be performed with 3 sets of 10 repetitions. the home based exercises will be modified every four weeks to different and challenging exercises. adherence for the home based sessions will be measured via determine the number of sessions done for both supervised and unsupervised (home based). Participants are required to maintain a diary to record the number of sessions done for the home based sessions.


Locations(1)

NSW, Australia

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ACTRN12614000517673