RecruitingACTRN12614000601639

Cultural Influence of Postoperative Pain

A prospective cohort comparing post-operative opioid requirement and other pain related behaviours and effects after major surgery in two Chinese populations from Hong Kong and Mainland China


Sponsor

Dr Alex Konstantatos

Enrollment

250 participants

Start Date

Oct 24, 2013

Study Type

Observational

Conditions

Summary

We hypothesize that cultural differences within the same race (Chinese) will lead to changes in opioid requirement after major abdominal surgery. This will be reflected by the differences in briefs and attitudes towards postoperative pain between patients living in the two cities.


Eligibility

Sex: Both males and femalesMin Age: 18 YearssMax Age: 80 Yearss

Inclusion Criteria4

  • Patients are eligible for the study if
  • 18 and 80 years
  • undergoing major abdominal surgery requiring a wound incision > 10 cm in length.
  • All patients should have strong Chinese features and lived in their respective cities (Hong Kong or Hangzhou) for most of their lives.

Exclusion Criteria5

  • Patients are excluded if they:
  • do not agree to receive patient controlled analgesia (PCA) with morphine for at least three days after surgery
  • do not demonstrate adequate understanding on the principles involving the use of PCA during the preoperative visit.
  • Allergy to morphine, paracetamol or non-steroidal anti-inflammatory drugs.
  • Patients with pre-existing severe renal and liver disease, 5. chronic pain for > 3 months in the 6 months leading to surgery or who require opioid therapy in the preceding 2 weeks prior to surgery

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Interventions

Observational cohort study of pain perception and opioid requirements post major abdominal surgery in chinese adults that are culturally different. Observations will occur preoperatively and then twi

Observational cohort study of pain perception and opioid requirements post major abdominal surgery in chinese adults that are culturally different. Observations will occur preoperatively and then twice daily for 3 days postoperatively.


Locations(2)

Zhejiang, China

Shatin, Hong Kong

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ACTRN12614000601639