RecruitingACTRN12614000638639

Perfusion index as a predictor for optimum positive end -expiratory pressure in Acute Respiratory Distress Syndrome patients management

Perfusion index as a predictor for optimum positive end-expiratory pressure(PEEP) in acute respiratory distress syndrome(ARDS) patients management


Sponsor

South valley university

Enrollment

40 participants

Start Date

May 5, 2014

Study Type

Interventional

Conditions

Summary

We will study the relation between perfusion index and optimum positive end expiratory pressure in Acute respiratory distress syndrome patients management.


Eligibility

Sex: Both males and femalesMin Age: 18 YearssMax Age: 65 Yearss

Plain Language Summary

Simplified for easier understanding

Patients in the intensive care unit (ICU) with a condition called Acute Respiratory Distress Syndrome (ARDS) — where the lungs become severely inflamed and fill with fluid — need help breathing through a ventilator. A key part of ventilator care is choosing the right level of positive end-expiratory pressure (PEEP), which keeps the air sacs in the lungs open. This study is testing whether a simple monitoring tool — the perfusion index (a measure of blood flow) — can help doctors find the ideal PEEP setting more effectively. You may be eligible if: - You are between 18 and 65 years old - You are in the ICU with ARDS caused by a lung condition such as severe pneumonia You may NOT be eligible if: - Your ARDS was caused by a condition outside the lungs - You have a collapsed lung (pneumothorax) - You have a bleeding or clotting disorder - You have congestive heart failure or cardiogenic pulmonary oedema - You are haemodynamically unstable Talk to your doctor about whether this trial might be right for you.

This is a simplified summary. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

We will titrate the PEEP level from baseline(5cm.H2O) by increments of 2cm.H2O for 30 minutes for each PEEP level till reaching the value of optimum PEEP that corresponds to best oxygenation(Pao2-sao

We will titrate the PEEP level from baseline(5cm.H2O) by increments of 2cm.H2O for 30 minutes for each PEEP level till reaching the value of optimum PEEP that corresponds to best oxygenation(Pao2-sao2 and hypoxic index ) and correlates it with the perfusion index changes in ARDS patients.


Locations(2)

Qena, Egypt

Mansoura, Egypt

View Full Details on ANZCTR

For the most up-to-date information, visit the official listing.

Visit

ACTRN12614000638639