CompletedPhase 4ACTRN12614000758606

Effects of Sevoflurane and Desflurane on otoacoustic emissions (OAE) in healthy adult patients with normal hearing tests undergoing septoplasty and turbinoplasty surgery


Sponsor

Gurcan Gungor

Enrollment

22 participants

Start Date

Jun 20, 2012

Study Type

Interventional

Conditions

Summary

To determine the influence of the new short acting inhalation agents;desflurane and sevoflurane which are widely used in general anaesthesia on otoacoustic emissions (OAEs) in humans. Otoacoustic emissions measured under desflurane and sevoflurane anaesthesia. Both agents effect the systemic blood pressures and OAEs. Desflurane and sevoflurane effect OAE measurements by several mechanisms


Eligibility

Sex: Both males and femalesMin Age: 20 YearssMax Age: 50 Yearss

Inclusion Criteria1

  • Healthy patients with normal hearing tests who underwent septoplasty and turbinoplasty surgery

Exclusion Criteria2

  • abnormal hearing test
  • TEAOE levels less than 3 dB SPL ( decibel -Sound pressure level ) or DPOAE levels less than 6 dBSPL in the preoperative measurements

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Interventions

Arm 1: sevoflurane 2% by inhalation from induction until the end of the operation Arm 2: desflurane 5% by inhalation from induction until the end of the operation

Arm 1: sevoflurane 2% by inhalation from induction until the end of the operation Arm 2: desflurane 5% by inhalation from induction until the end of the operation


Locations(1)

Turkey

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ACTRN12614000758606