Dexmedetomidine Versus Nefopam for management of post spinal anesthesia shivering:A randomized double-blind controlled study
Dexmedetomidine Versus Nefopam for management of post spinal anesthesia shivering
South valley university
100 participants
Nov 1, 2014
Interventional
Conditions
Summary
We will compare dexmedetomidine and Nefopam for treatment of postspinal anesthesia shivering regarding time of stoppage of shivering,effective postspinal anesthesia time .
Eligibility
Inclusion Criteria1
- ASA I and II patients scheduled for elective lower abdominal,lower limb , orthopedic and plastic surgeries under spinal anesthesia
Exclusion Criteria1
- Known hypersensitivity to dexmedetomidine or Nefopam,cardiopulmonary,renal or hepatic diseases,patients with a contra indication to spinal anesthesia e.g coagulation disorders,patients with failed or partial spinal block or those who do not agree to participate in the study
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Interventions
dexmedetomidine in a dose of 0.5Ug/Kg intravenous(i.v.) or Nefopam in a dose of 0.15mg/Kg I.v. In the respective groups.each drug was diluted into 5 ml by isotonic saline and given by slow I.v.( one minute) at the onset of shivering.either of the two drugs was given according to the group in the postoperative spinal anesthesia period to patients who develop grade III or IV shivering . When shivering recures additional dose of either of the two drugs according to the group can be given as the same previous dose and recorded.
Locations(1)
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ACTRN12614001124628