Routine Use Of 0.9% Saline Vs. Routine Use Of Plasma-Lyte 148 (Registered Trademark) For Intravenous Fluid Therapy In Emergency Department Patients
Routine Use Of 0.9% Saline Vs. Routine Use Of Plasma-Lyte 148 'Registered Trademark' For Intravenous Fluid Therapy In Emergency Department Patients: a comparison of kidney function, hospital length of stay, intensive care admission and mortality.
Medical Research Institute of New Zealand
3,000 participants
Jan 1, 2015
Interventional
Conditions
Summary
This will be an audit to provide preliminary data to address whether the use of Plasma-Lyte148 'Registered Trademark' as default intravenous fluid results in better clinical outcomes compared to current standard practice. The audit will be conducted with two 12 week periods. During the control period patients admitted to Wellington Regional Hospital from ED would have received intravenous fluid at the discretion of the treating doctors, in which 0.9% saline would have been the preferred intravenous fluid. This will be compared a 12 weeks where the preferred fluid will be Plasma-Lyte148 'Registered Trademark'. The outcomes that will be recorded will be kidney function, hospital length of stay, intensive care admission and mortality.
Eligibility
Inclusion Criteria1
- Patients >18 year presenting to ED and subsequently admitted to hospital who have a serum creatinine measured in the ED
Exclusion Criteria1
- Patients on renal replacement therapy for end stage renal failure.
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Interventions
Single centre, open label, before and after audit. One month prior to the intervention period there will be Emergency Department (ED) staff education and logistic arrangements for changing to Plasma-Lyte 148 'Registered Trademark' as the default IV fluid. During the 12 week intervention period Plasma-Lyte 148 'Registered Trademark' will be used as the default primary crystalloid fluid. The dosing regimen is at the discretion of the treating clinician. A random sample of 100 patients that received fluid in emeregency department will be assessed to see extact type and amount of given.
Locations(1)
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ACTRN12614001178639