Effect of purple Plum juice on blood pressure in overweight/obese participants.
The effect of Prunus salicina (Queen Garnet) Plum juice on blood pressure in mild hypertensive overweight/obese subjects.
A/Prof Michael Mathai
70 participants
Jun 16, 2015
Interventional
Conditions
Summary
Metabolic syndrome is characterised by a cluster of cardiovascular risk factors, including central obesity, elevated blood pressure, dyslipidemia (low HDL cholesterol, high triglyceride levels & LDL cholesterol) and elevated plasma glucose levels. Individuals with metabolic syndrome have central obesity and at least one other risk factor to be clinical diagnosed with the syndrome. Metabolic syndrome is an emerging clinical challenge and imperative public health issue. Subjects with metabolic syndrome have a markedly increased risk of cardiovascular mortality. Prunus salicina, Queen Garnet plum (QGP), is a fruit that was naturally bred to have a high anthocyanin and antioxidant content, in a Queensland Government agriculture initiative. Queen Garnet plums showed anti-obesigenic properties. Studies in laboratory animals have shown that treatment with Queen Garnet plum juice improved the unhealthy blood lipid profile caused by a high-carbohydrate, high-fat diet. The primary object for this study is to monitor blood pressure changes with Queen Garnet plum juice. Blood pressure is measured by using an automatic sphygmomanometer for 12 weeks of duration.
Eligibility
Inclusion Criteria1
- Participants will need to be overweight with a BMI of greater than 25 or a waist circumference >94cm (male), >80cm (female), systolic blood pressure 130-159 mmHg and diastolic blood pressure 85-99 mmHg.
Exclusion Criteria1
- Liver, kidney and heart disease, pregnancy, type 1 diabetes, type 2 diabetes with any medication, cigarette smoking and the use of any medication for weight loss or hypertension.
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Interventions
Queen garnet plum juice is made from a fresh plums by Department of Agriculture, Fisheries and Forestry, Queensland, Australia. All participants will be requested to drink 200 ml/day juice every morning for a duration of 12 weeks. All participants will be given a juice calendar and were requested to fill in juice calender, every day after drinking juice. Participants were also requested to return the empty juice bottles during their visit to Nutrition clinic every fortnight.
Locations(1)
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ACTRN12614001270606