CompletedPhase 2ACTRN12615000028505

A prospective, single arm, single centre pilot trial to establish the safety and efficacy of the Oventus device to treat mild to moderate obstructive sleep apnoea and snoring.


Sponsor

Oventus Pty Ltd

Enrollment

30 participants

Start Date

Mar 3, 2015

Study Type

Interventional

Conditions

Summary

The purpose of the study is to reduce the symptoms of mild to moderate obstructive sleep apnoea (OSA) and snoring using the Oventus oral appliance. Sleep apnoea is assigned an apnoea hypopnoea index (AHI) number which indicates the severity of OSA. The aim of the study is to reduce AHI by at least 50% in at least 20% of the participants in the study.


Eligibility

Sex: Both males and femalesMin Age: 18 Yearss

Inclusion Criteria1

  • Age equal to or greater than 18, mild to moderate AHI (between 5-30), eligible to receive a mandibular advancement device, grade 2-3 snoring, intact top row of teeth, able top provide written consent and adhere to protocol requirements.

Exclusion Criteria1

  • Pregnant or lactating females, participating in another clinical trial, periodontal disease, exaggerated gag reflex, medication usage that could influence respiration or sleep, obstructive sleep apnoea with uncontrolled or untreated cardiovascular disease, central sleep apnoea events greater than 5 per hour.

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Interventions

Oventus oral mandibular advancement device is worn during sleep. It is anticipated that the device will be worn between 6-8 hours per night every night for 2-6 weeks (determined by patient preference)

Oventus oral mandibular advancement device is worn during sleep. It is anticipated that the device will be worn between 6-8 hours per night every night for 2-6 weeks (determined by patient preference). Device fitting will take 1-2 hours during the initial fit and may be adjusted up to 4 times during the study which will take a further 30-60 minutes each adjustment.


Locations(1)

QLD, Australia

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