RecruitingACTRN12615000261516

Apnoeic Oxygenation: A Comparison of Nasal Prongs to Nasopharyngeal Cannula on oxygenation before Intubation

A comparison of fraction of inspired oxygen (FiO2) levels at the pharyngeal inlet due to the application of oxygen via either nasal prongs or nasopharyngeal cannula during apnoea, prior to intubation in patients undergoing elective surgery at Monash Health.

Sponsor

Department of Anaesthetics, Southern Health

Enrollment

44 participants

Start Date

Aug 10, 2015

Study Type

Interventional

Conditions

Prevention of Oxygen desaturation during intubation

Summary

Update The research project is comparing different devices for giving oxygen during the start of an anaesthetic. The different devices are called nasal prongs and nasopharyngeal cannula. Nasal prongs and nasopharyngeal cannula are already approved in Australia to supply Oxygen to patients in hospital. All participants will receive Oxygen through a face mask before they are put to sleep for an operation. In addition, participants may receive additional Oxygen through nasal prongs or nasopharyngeal cannula. You will then be given anaesthetic medication and will go to sleep as normal. In this study, we would like to see how patients’ Oxygen levels in their throat change once they are asleep, enabling us to compare the different devices in terms of their effectiveness and the extent to which they can increase oxygen levels. Our hypothesis is that each of the devices will increase Oxygen levels and we aim to determine if there is any difference between these two devices with respect which may be more effective at delivering Oxygen for this purpose.

Eligibility

Sex: Both males and femalesMin Age: 16 Yearss

Plain Language Summary

Simplified for easier understanding

This study is comparing two different devices for delivering extra oxygen to patients just before they are put under general anaesthesia and have a breathing tube placed. The two devices are nasal prongs (small tubes placed in the nostrils) and a nasopharyngeal cannula (a slightly longer tube placed further back in the nose). Both devices are already approved for use in hospitals. The study aims to find out which device more effectively maintains oxygen levels during this brief period. You may be eligible if: - You are 16 years of age or older - You are having surgery at Southern Health and need a breathing tube placed as part of your anaesthetic - Your oxygen levels on room air are above 94% - You are willing to give informed consent You may NOT be eligible if: - You are under 16 years old - You are pregnant - Your oxygen levels on room air are below 94% Talk to your doctor about whether this trial might be right for you.

This is a simplified summary. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Print for Your Doctor Check Your Eligibility

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

Our study compares the application of oxygen via nasal prongs to nasopharyngeal cannula during the period of apnoea, prior to intubation. Nasal prongs are a non-invasive means of delivering oxygen.

Our study compares the application of oxygen via nasal prongs to nasopharyngeal cannula during the period of apnoea, prior to intubation. Nasal prongs are a non-invasive means of delivering oxygen. They are comprised of a lightweight tube with two small prongs, each of which enters the nostrils, through which a mixture of oxygen and air is delivered. It is connected to an Oxygen supply. Nasopharyngeal cannula is a longer, flexible tube which is passed through a single nostril, further into the upper airway until the tip comes to rest at the oropharyngeal inlet. This is also non-invasive and is connected to an oxygen supply so that air and oxygen can be delivered through it. We will apply the chosen device to our patients before anaesthetic induction and provide normal pre-oxygenation. Oxygen will then run through the devices at 15Litres/minute. This will flow for three minutes, after the patient stops breathing and before intubation is attempted. Normally, no devices are applied to the patient during this period. The concentration of oxygen (Fi02) at the pharyngeal inlet is measured just prior to intubation. We will compare these values.

Locations(2)

Monash Medical Centre - Clayton campus - Clayton

VIC, Australia

Monash Medical Centre - Moorabbin campus - East Bentleigh

VIC, Australia

View Full Details on ANZCTR

For the most up-to-date information, visit the official listing.

Visit

ACTRN12615000261516