Evaluation of intravenous fluid resuscitation with either 4% albumin or 20% albumin solution for patients admitted to the intensive care unit

This clinical trial is studying: Evaluation of intravenous fluid resuscitation with either 4% albumin or 20% albumin solution for patients admitted to the intensive care unit. This study is open to both male and female participants. Participants must be at least 18 years old. You may be eligible if: - Admitted to the Department of Intensive Care, Austin Hospital for less than 48 hours or to the Intensive and Critical Care Department of the Flinders Medical Centre for less than 48 hours - Age 18 years or greater - Need for fluid bolus as determined by the treating clinician - Presence of one or more of the following physiological states: systolic BP <90 mmHg, or MAP <65 mmHg, or increasing need for vasopressor drug infusion or pulse pressure variation >12 % or stroke volume variation >12%, or Cardiac index <2.2 L/min/m2 or heart rate >100 or urinary output <20 ml/hr or either rising lactate levels or lactate levels >2 mmol/L or capillary refill time >3 seconds or central venous pressure <8 mmHg You may NOT be eligible if: - Confirmed or suspected pregnancy - Patients with traumatic brain injury - Active bleeding - Haemoglobin level <70 g/L - People who refuse blood products - Patients in whom death is considered imminent (within 24 hours) Talk to your doctor to see if this trial is right for you.