Effect of lumbar anaesthesia on sympathetic activity below the level of the block
Area under curve of the photoplethysmographic signal as the evaluation measure for sympathetic activity during lumbar epidural anaesthesia
Clinical Hospital Center Zagreb
40 participants
May 4, 2015
Interventional
Conditions
Summary
Photoplethysmographic signal reflects sympathetic activity under the level of epidural block. The height of sensory block during epidural anaesthesia reflects the height of sympathetic block. Area under the photoplethysmographic curve (AUC) depends on variability of the photoplethysmographic signal strenght and duration. Our hypothesis is that change in any parameter, due to the sympathetic block, will change the area under the curve of the photoplethysmographic signal. 40 patients with epidural anaesthesia will be included in the research. 0.5% bupivacaine will be injected in the L3/L4 level and Biopac SS4LA Pulse Plethysmograph Transducer will be used for photoplethysmography recording. Amplitude (maximum PPG sygnal), pulse transit time and area under the curve will be recorded. Our goal is to test sympathetic activity using variabilities, shapes and characteristics of the PPG curve (area under the curve) during 0.5% bupivacaine epidural anaesthesia.
Eligibility
Inclusion Criteria1
- patients aged 18-45 which underwent surgical procedure under epidural anaesthesia.
Exclusion Criteria4
- pulses of the arteria tibialis posterior and arteria dorsalis pedis are not palpable
- perspiration of the feet is not maintained
- abnormal growth and transparency of the nails
- changes which indicate pathological alteration of the blood vessels of the lower extremities
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Interventions
Only one group of patients was included in the study. 0.5% bupivacaine was injected in the L3/L4 level by the qualified anaesthesiologist and Biopac SS4LA Pulse Plethysmograph. Photoplethysmography recordings were taken before lumbar epidural anaesthesia procedure was done, as well as during the whole surgical procedure and during the post-anaesthesia recovery (until all of the sensoric functions of the lower limbs were recovered). Transducer was used for photoplethysmography recording. Amplitude (maximum PPG sygnal), pulse transit time and area under the curve were recorded.
Locations(1)
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ACTRN12615000538549