Comparative assessment of the absorption of 3 generic formulations of isotretinoin capsules against the innovator isotretinoin capsule in a pilot study conducted under fasting conditions in healthy male volunteers

This clinical trial, titled "Comparative assessment of the absorption of 3 generic formulations of isotretinoin capsules against the innovator isotretinoin capsule in a pilot study conducted under fasting conditions in healthy male volunteers," is a research study looking for volunteers to participate. This study is specifically for males. Participants should be between 18 years and 55 years of age. You may be eligible if: - Healthy males - Aged between 18 and 55 years - Non-smoker - BMI greater than or equal to 19 and less than 30 inclusive - Normal, healthy individuals as determined by medical history, physical examination, ECG, blood pressure and laboratory tests - Drug free as determined by urine drug testing - Able to comply with the study restrictions - Able to provide written information consent You may NOT be eligible if: - Females - History of recent recurrent attacks of bronchitis, asthma or migraine headaches - Concomitant drug therapy of any kind - Received an investigational compound or drug known to induce or inhibit liver enzymes within 60 days of the start of the study - History of depression or other mental illness, or a history of epilepsy or seizures - History of conditions that might interfere with the absorption, distribution, metabolism or excretion of the drug - History of alcohol or drug abuse or dependency - Sensitivities to Vitamin A or food such as liver Talk to your doctor to see if this trial is right for you. Your doctor can help you understand the potential benefits and risks, and whether your health situation matches what the researchers are looking for.