A prospective, contralateral lens wear, randomised, controlled, 3-months clinical trial to test the efficacy and safety of a surface modified contact lens during continuous wear modality.

Exclusion Criteria10

• Any pre-existing ocular irritation, injury or condition (including keratoconus and herpes keratitis) of the cornea, conjunctiva or eyelids that would preclude contact lens fitting and safe wearing of contact lenses;
• Any systemic disease that adversely affects ocular health e.g. diabetes, Graves’s disease, and auto-immune diseases such as ankylosing spondylitis, multiple sclerosis, Sjögrens syndrome and systemic lupus erythematosis. Conditions such as systemic hypertension and arthritis do not automatically exclude prospective participants;
• An active corneal infection or any active ocular disease that would affect wearing of contact lenses;
• Use of or a need for any therapeutic ocular medication at enrolment (that would be required to be discontinued during the study);
• Use of or a need for any systemic medication or topical medications which may alter normal ocular findings/are known to affect a participant’s ocular health/physiology or contact lens performance either in an adverse manner or risk providing a false positive.
• Eye surgery within 12 weeks immediately prior to enrolment for this trial.
• Previous corneal refractive surgery.
• Known allergy or intolerance to ingredients in any of the study products.
• Currently enrolled in another clinical trial or participation in a clinical trial within the previous 2 weeks.
• Pregnancy or lactating (Testing of pregnancy is not required. A participant’s verbal report is sufficient).