Evaluating the Cough Evoked Response on emergence in patients undergoing general anaesthesia trial (ECER TRIAL)

The aim of this study is to compare the incidence of cough response during emergence in general anaesthesia with sugammadex or neostigmine as the reversal agent. We hope this study will help and guide clinicians to choose a safe and appropriate drug that can efficiently reverse the patient under general anesthesia with minimal risk of coughing on emergence and other adverse events. Hypothesis: Reversal of neuromuscular blockade with either sugammadex or neostigmine at the end of neurosurgery will result in difference in the grade of cough response during emergence. Different dosage of sugammadex used for reversal may have different outcome in cough response.