CompletedPhase 4ACTRN12616000479404

The effect of anthropometric characteristics on the spread of hyperbaric bupivacaine spinal anaesthesia in patients undergoing lower abdominal or lower extremity surgery.

The effect of anthropometric characteristics on the spread of spinal anesthesia with 0.5% hyperbaric bupivacaine in patients undergoing lower abdominal or lower extremity surgery


Sponsor

Mehmet Canturk

Enrollment

60 participants

Start Date

Oct 15, 2015

Study Type

Interventional

Conditions

Summary

Background:Several factors have been described to effect the spread of spinal anesthesia. Clinical sense says that patients with a larger hip size and a narrow shoulder size have a relative trendelenburg position on a horizontal operation table that results in more cephalad spread of the hyperbaric local anesthetic solution although there is no clinical study reporting the effect of hip/shoulder size ratio on the spread of spinal anesthesia.We hypothesized that the increase in cephalad spread is strongly correlated with the increased hip/shoulder size ratio. Methods: Age, weight, height, body mass index, hip size, shoulder size, hip/shoulder size ratio, vertebral column length were recorded for 75 patients. The L4-L5 interspace was introduced at lateral position on a horizontal operation table with a 25G spinal needle and 3ml 0.5% hyperbaric bupivacaine was injected intrathecal in 15 seconds without barbotage and patient was turned supine 5 minutes after intrathecal injection. Pearson and Sperman’sRho Correlation Tests were performed for the relation between age, height, weight, body mass index, hip size, hip/shoulder size ratio, shoulder size and vertebral column length and the multiple regression analysis was used to test the combined contribution of the above variables on cephalad spread of spinal anesthesia. Results:We determined a positive correlation with hip/shoulder size ratio (r = 0, 40; p = 0,002), and a negative correlation with the height (r= -0, 29; p=0,026), and the shoulder size (r= -0, 31; p= 0,017) of the patients with the cephalad spread ofspinal anesthesia. Multiple regression analysis showed that hip size and the hip/shoulder size ratio were the important determinants for the cephalad spread of spinal anesthesia and the other variables had no effect. Conclusions: The cephalad spread of spinal anesthesia with a fixed dose of hyperbaric bupivacaine is affected by the ratio of hip/shoulder size, shoulder size and the height of the patient. Vertebral column length has no effect on spinal anesthesia spread.


Eligibility

Sex: Both males and femalesMin Age: 18 YearssMax Age: 75 Yearss

Inclusion Criteria1

  • patients approving spinal anesthesia and the study protocol for the surgery that he/she is undergoing( either lower extremity or lower abdominal surgery).

Exclusion Criteria1

  • patients refusing spinal anesthesia or the study protocol, any contraindication for spinal anesthesia, age greater than 75 years or smaller than 18 years

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Interventions

3 ml 0.5% hyperebaric bupivacaine was injected intrathecally in 15 seconds wiithout barbotage as a single dose from L4-L5 interspace of spinal canal by an anesthesiologist. The dose administered was c

3 ml 0.5% hyperebaric bupivacaine was injected intrathecally in 15 seconds wiithout barbotage as a single dose from L4-L5 interspace of spinal canal by an anesthesiologist. The dose administered was controlled by the study staff as a standard dose of 3ml according to study protocol. Surgery started when the level of spinal anesthesia reached to T10 dermatome


Locations(1)

kirsehir, Turkey

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ACTRN12616000479404