Comparison of minimally invasive cardinal/uterosacral ligament plication and oral tropsium chloride for urinary urge incontinence in women.

This trial is comparing two treatments for women with urge urinary incontinence — the sudden strong urge to urinate that leads to leaking. The first treatment is a bladder relaxant medication (trospium chloride taken as a pill). The second is a minimally invasive day-surgery procedure that tightens the ligaments supporting the bladder and uterus. Both approaches are tested in a randomised controlled trial, with follow-up surveys at 6, 12, and 26 weeks. You may be eligible if: - You are a woman aged 21 or older - You have urge incontinence (involuntary leaking with urge to urinate) two or more times per day on an average day - You have a mild to moderate prolapse of the bladder or uterus (POPQ grade 1–3) - Your symptoms improve slightly when a speculum is gently inserted into the back of your vagina (a test done in clinic) You may NOT be eligible if: - You have a severe (grade 3 or 4) uterine prolapse - You have a current urinary tract infection - You have a known neurological condition such as multiple sclerosis - You have had previous vaginal surgery other than a midurethral sling or hysterectomy Talk to your doctor about whether this trial might be right for you.