Combination with Sevoflurane Anesthesia Attenuates Nasopharyngeal Secretions in Propofol-Based Total Intravenous Anesthesia in Ocular Surgery

In the propofol/sevoflurane group, the anesthesia induction were as the total intravenous anaesthesia (TIVA) group patients, whereas anesthesia was maintained using intravenous propofol infusion and 1% sevoflurane (inhaled concentration) with with 50% oxygen flow of 1 mL/min by the treating anaesthetist. Maintenance of the effect-site concentration (Ce) for the propofol/sevoflurane was adjusted to keep BIS value between 40–60 and mean arterial blood pressure at 80–100 mm Hg determined by the treating anaesthetist. The EtCO2 pressure was maintained at 35-45 mmHg. Once neuromuscular function returns, rocuronium (0.1 mg/kg, intravenously [i.v.]) was administered as required by the treating anaesthetist. All patients received i.v. methasone 0.1 mg/kg for preventing post-operative nausea and vomiting (PONV) while induction of anaesthesia by the treating anaesthetist.. At the end of the procedure, propofol or sevoflurane was discontinued and the lungs were ventilated with 100% oxygen at a fresh gas flow of 6 L/min by the treating anaesthetist. Reversal of neuromuscular function was achieved by administrating neostigmine (0.03-0.04 mg/kg, i.v.) with glycopyrrolate (0.006-0.008 mg/kg, i.v.) once spontaneous breathing returned to prevent residual paralysis at the clinical discretion of the treating anaesthetist. When the patient regained consciousness by name with spontaneous and smooth respiration, the endotracheal tube was removed and the patient was sent to the postoperative anesthesis care unit for further care.