Randomised placebo controlled trial of inhaled corticosteroids for treatment of chronic cough in children.
Is a two week course of inhaled corticosteroids efficacious for reducing cough severity in children with chronic cough, compared to placebo?
Prof Anne Chang
77 participants
Jun 7, 2011
Interventional
Conditions
Summary
This study will help us answer the question: should children with chronic cough be given inhaled corticosteroids to promote faster recovery and improve ability for children to return to their normal daily routines? This study will also evaluate whether fractional exhaled nitric oxide levels can predict short term response to inhaled corticosteroids in children with chronic cough. We hypothesise that a short (two week) course of inhaled corticosteroids will reduce cough severity in children with chronic cough, and that FeNO measurements can be used to predict this response.
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
Children will be randomised to receive either inhaled corticosteroids or placebo. Children allocated to the intervention group will receive 250 micrograms fluticasone propionate twice daily for two weeks, delivered via metered dose inhaler and spacer (with or without mask, depending on age and technique).
Locations(2)
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ACTRN12616001713482