Rapid Iron Infusion Study- a randomised controlled trial (RCT) of the treatment of iron deficiency anaemia in children (RIIS)

This study tests whether a single intravenous (IV) iron infusion given over 15 minutes can treat iron deficiency anaemia better than the current standard treatment of intramuscular (IM) iron injections in young Aboriginal and Torres Strait Islander children. Iron deficiency anaemia in early childhood affects brain development and immunity. IV infusion with a drug called ferric carboxymaltose (Ferinject) may boost haemoglobin levels faster, reduce the number of painful injections, and improve adherence to treatment compared with repeated IM injections. You may be eligible if: - Your child is Aboriginal or Torres Strait Islander - Your child has iron deficiency anaemia (haemoglobin below 110 g/L and low mean cell volume below 75 fL) - Your child's treating clinician has recommended parenteral (injectable) iron treatment - Your child is 6 years of age or younger You may NOT be eligible if: - Your child has received injectable iron or a blood transfusion in the past 4 weeks - Your child has a known blood disorder (e.g., thalassaemia) or iron overload - Your child has a fever above 38°C or is very unwell at discharge - Your child has a known allergy to Ferinject or similar iron products - Your child has severe asthma or allergies - Your child will not remain in the Northern Territory for 12 months Talk to your doctor about whether this trial might be right for you.