Intravitreal Aflibercept for the Treatment of Treatment Resistant Macular Oedema secondary to Retinal Vein Occlusions

This study is for people who have a swelling in the back of the eye (macular oedema) caused by a blocked retinal vein, and who have not responded well to existing eye injection treatments. Researchers want to find out if switching to a different medication called aflibercept (Eylea) can reduce the swelling and improve vision. You may be eligible if: - You are aged 18 or older - You have macular oedema caused by a blocked retinal vein (retinal vein occlusion) - You have already received at least 4 anti-VEGF injections over 6 months with ongoing swelling - Your vision in the affected eye is between 6/12 and 6/120 You may NOT be eligible if: - You are pregnant or breastfeeding - You are a pre-menopausal woman not using contraception - You have had an eye injection in the study eye within the past 30 days - You have had eye surgery in the past 2 months - You have had a stroke or heart attack in the past 3 months - You have uncontrolled diabetes (HbA1c above 12%) or very high blood pressure (above 180/110) - Your vision loss is due to another cause such as macular degeneration Talk to your doctor about whether this trial might be right for you.