Use of antibiotic prophylaxis in the prevention of postoperative infection of third impacted mandibular molars
Antibiotic Prophylaxis in the prevention of infectious complications in mandibular impacted third molars extraction: A randomized clinical trial
Facultad de Odontología. Universidad de Chile
120 participants
May 2, 2016
Interventional
Conditions
Summary
Third molar surgery is the most frequent procedure in oral and maxillofacial surgery. Surgical wound infection is the most prevalent complication. Determine if the use of 2 gr. of Amoxicillin as AP reduces the proportion of postoperative infectious complications in the impacted third molar extraction compared to placebo. To determine the proportion of postoperative infectious complications of the experimental group (2 gr Amoxicillin) and control group (placebo) derived from the exodoncia of impacted mandibular third molars. To compare the proportion of postoperative infectious complications of the experimental group versus the control group. To compare the proportion of rescue medication requirement associated with postoperative pain between the experimental group versus the control group. Describe any adverse reactions resulting from the use of 2 gr. Amoxicillin as AP.
Eligibility
Inclusion Criteria1
- Healthy patients between 15 to 35 years old: Clinically and radiographically presence at least of one impacted mandibular third molar,
Exclusion Criteria9
- Pregnancy.
- Allergy to penicillin and its derivatives.
- Allergy to nonsteroidal anti-inflammatory drugs.
- Patients with gastric ulcer.
- Patients who have undergone any type of antibiotic treatment at least 30 days before surgery.
- Patients with pericoronaritis episode up to 7 days before the intervention.
- Patients with psychiatric illness.
- Immunocompromised
- Patients with addiction to narcotic drugs or illicit substances
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Interventions
2 gr. Amoxicillin one hour before the surgery . Oral tablet
Locations(1)
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ACTRN12617001498381