Smoking cessation and effects of cigarette smoking on cure and side effects of treatment in patients with cancer in the head and neck region.

This study is looking at how quitting smoking affects the outcomes of treatment for head and neck cancer. Head and neck cancers include cancers of the mouth, throat, voice box, and nasal passages. Researchers will track whether patients who stop smoking during or after treatment do better than those who continue — including how well the treatment works, side effects, and survival rates. Participants will be followed up for up to 5 years after treatment. You may be eligible if: - You are 18 years or older - You have been diagnosed with squamous cell carcinoma of the oral cavity, pharynx, larynx, nasal cavity, or paranasal sinuses (Stage I–IV, no distant spread) - You are receiving curative treatment at Townsville Cancer Centre - You are in good enough health to undergo curative treatment (ECOG Performance Status 0–1) - You are of any smoking status (smoker or non-smoker) You may NOT be eligible if: - Your cancer type is not squamous cell carcinoma - Your cancer has spread to distant parts of the body (metastatic) - You are pregnant - Your cancer has come back (recurrent disease) - You have previously had radiation therapy to the head and neck region Talk to your doctor about whether this trial might be right for you.