Proton Density Fat Fraction MRI to estimate liver iron content

This study is comparing two types of MRI scans to see how well each one can measure the amount of iron stored in the liver. Having too much iron in the liver can cause organ damage and needs to be monitored. The study compares a newer, less expensive technique called Proton Density Fat Fraction MRI (PDFF) against a more expensive but well-established test called Liver FerriScan. If the cheaper test works just as well, doctors may be able to use it more widely to monitor patients with high iron levels. You may be eligible if: - You have a confirmed high blood ferritin level (above 500 µg/L on two tests taken 4 weeks apart) You may NOT be eligible if: - There are other possible causes of high ferritin that have not yet been investigated (e.g. infection or cancer) - You have a condition that prevents you from having an MRI (e.g. claustrophobia, pacemaker, or metal implants) - You have a terminal illness with a life expectancy of less than 3 months Talk to your doctor about whether this trial might be right for you.