CompletedPhase 3Phase 4ACTRN12618001661268

Effects of Moringa oleifera leaf powder supplementation in pregnant mothers on maternal and birth outcomes.

Effects of Moringa oleifera leaf powder supplementation in pregnant mothers on maternal health and birth weight in Jeneponto District, South Sulawesi Indonesia.


Sponsor

Prof. Veni Hadju

Enrollment

20 participants

Start Date

Jan 24, 2018

Study Type

Interventional

Conditions

Summary

The purpose of the study was to assess the effect of Moringa oleifera (MO) leaf powder supplementation in pregnant mothers on maternal health and birth weight. We hypothesized that anaemic pregnant mothers who received two grams of MO capsuled are better in haemoglobin level, stress, cortisol level, and birth weight compared to mothers who received a conventional iron folic acid intervention. Pregnant mothers were randomly divided into two groups, group received MO two capsules twice daily and group received iron folate with similar colour capsules for eight weeks. Measurements were performed by trained field workers before and after intervention for anthropometric, haemoglobin level, maternal stress, and cortisol level. Weight of the baby was measured at birth.


Eligibility

Sex: FemalesMin Age: 17 YearssMax Age: 41 Yearss

Inclusion Criteria4

  • Hemoglobin between 10 to 11gr/dl
  • Age of pregnancy is equal or above 28 weeks
  • Parity is equal or less than three
  • Willing to participate into the study

Exclusion Criteria3

  • Mothers who consumed other supplements.
  • Mothers with pregnancy complications such as hypertension, diabetes, others)
  • Mothers with bleeding.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

This is an intervention study about providing Moringa oleifera (MO) leaf powder capsules to the pregnant mothers. Study location was in Tamalatea sub-district, Jeneponto districts, South Sulawesi. It

This is an intervention study about providing Moringa oleifera (MO) leaf powder capsules to the pregnant mothers. Study location was in Tamalatea sub-district, Jeneponto districts, South Sulawesi. It takes three hours by car from Makassar city, the capital city of South Sulawesi, to the study location. The subjects were pregnant mothers in the early third semester. First, pregnant mothers were measured for hemoglobin level by trained field workers. Then, mothers with anemia were taken into the study. Anemia was defined using WHO category which is less than 11mg/dl. For ethical reason, we took only those who had haemoglobin level between 10-11mg/dl. Measurements were performed before and after treatment for anthropometric, food intakes, stress status, and cortisol concentration in blood. Mothers were randomly divided into two groups based on order on enrolment; group received two capsules (each 500mg) of MO twice a days (MG, n=19) and group received two similar capsule (contained 60mg iron/30ug folic acid) (IG, n=19). The groups were categorized A and B but it was blinded to the field investigators which group contained MO or Iron/folic acid. Intervention was done for eight weeks. The field workers distributed the capsule every week and asking the empty bottle prior to giving the next bottle. Mothers were controlled for their capsule consumption by sending short massages or called by the field workers. The short message was sent first in the morning and second in the afternoon. The content of the short message was to remind mothers to take the capsule and they have to reply that they had taken it. The sentence in the morning was "Have you consumed the capsule this morning?" while the sentence in the afternoon was "Have you consumed the capsule this afternoon?" Most of the mothers replied directly to the short message at the same day (both morning and afternoon). When there were no reply of the short message from the mothers, the field workers gave a call. In general, the call was done only once at the afternoon. At birth, mothers were weight together with their babies.


Locations(1)

South Sulawesi, Indonesia

View Full Details on ANZCTR

For the most up-to-date information, visit the official listing.

Visit

ACTRN12618001661268