RecruitingACTRN12618001842257

Benefits and high patency endoscopic vein harvesting in a flap in patients with coronary heart disease undergoing coronary artery bypass surgery

Comparison complications and patency bypass grafts after endoscopic vein harvesting in flap versus open vein-graft harvesting in patients undergoing coronary artery bypass surgery.


Sponsor

Federal State Budgetary Scientific Institution “Tomsk National Research Medical Center of the Russian Academy of Sciences”

Enrollment

300 participants

Start Date

Nov 15, 2018

Study Type

Interventional

Conditions

Summary

The great saphenous vein still remains one of the most popular additional conduits among others because of the availability and ease of its open harvesting. All described methods of endoscopic venous harvesting are associated with "skeletonization" of an autovenous conduit . The scientific novelty of our work is that we propose to harvest a vein through one mini-incision with the help of Karl Storz endoscopic equipment and the Ligasure electrodissector with surrounding tissues without the use of carbon dioxide. Harvesting vein endoscopically, together with the surrounding tissues, makes it possible to reduce complication in the lower extremities and prolong the patency of the venous conduits by finding itself in the flap.


Eligibility

Sex: Both males and femalesMin Age: 45 YearssMax Age: 79 Yearss

Plain Language Summary

Simplified for easier understanding

When people have coronary artery bypass surgery (heart bypass), surgeons often need to use a vein from the leg to create the bypass. Traditionally, a long cut is made down the leg to harvest this vein, which can cause wound complications. This study is investigating a newer approach where the vein is removed through a single small incision using an endoscope and a special energy device, with the vein kept in a protective sleeve of surrounding tissue rather than being 'skeletonised'. The researchers believe keeping the surrounding tissue intact may reduce leg wound problems and help the bypass vein stay open longer. Participants undergoing coronary bypass surgery are assigned to either the new endoscopic technique or the standard method, and both groups are followed to compare healing of the leg wound, complications, and how well the bypass grafts stay open over time. You may be eligible if you have coronary artery disease and are scheduled for bypass surgery, with a body mass index similar to the overall study group (to control for wound healing differences related to weight). People having heart valve surgery at the same time, or those with varicose veins in the legs, are not eligible.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

A randomized study comparing two groups of vein harvesting methods for coronary artery bypass grafting (CABG): endoscopic harvest versus standard open techniques. Materials: Three hundred patients li

A randomized study comparing two groups of vein harvesting methods for coronary artery bypass grafting (CABG): endoscopic harvest versus standard open techniques. Materials: Three hundred patients listed for CABG Procedures: The endoscopic vein harvesting in flap are performed using an endoscopic video installation Karl Storz. the surgeon performs a cross-section of the skin 3 to 4 cm long at the level of the knee joint. And vein harvest from the leg using retractor (Freiburg model (Karl Storz) with endoscopic optics HOPKINS (Forward-Oblique Telescope 45 ° (Karl Storz). With the help of an electrical dissector, a tunnel is formed along the flap of a vein with a simultaneous harvesting of the flaps itself. Who: heart surgeon with 10 years experience Mode of delivery: face to face Number of times: twenty once/month for 4 months


Locations(1)

Russian Federation

View Full Details on ANZCTR

For the most up-to-date information, visit the official listing.

Visit

ACTRN12618001842257