RecruitingPhase 3Phase 4ACTRN12619000073101

Comparison of Efficacy of Oral Azithromycin Versus Oral Doxycycline in the Treatment of Moderate Acne Vulgaris and Determination of the Effects of These Treatments on Patients' Quality of Life Among University Students.


Sponsor

Sultan Qaboos University

Enrollment

200 participants

Start Date

Oct 1, 2019

Study Type

Interventional

Conditions

Summary

An open label randomised controlled trial which will be conducted in student clinic and comparing the efficacy of oral azithromycin and oral doxycycline on moderate acne plus it will see the difference in quality of life scale in both groups before and after treatment. A total of 200 moderate acne patients, males and females, will be included in the study, 100 patients in each arm. The gender and age will be distributed equally between the two groups. They will be followed for 3 months with an assessment in the improvement in acne severity scale every month from the start of the study. The response to treatment will be assessed by using the difference in acne severity scale before treatment and after 3 months of treatment.


Eligibility

Sex: Both males and femalesMin Age: 17 YearssMax Age: 25 Yearss

Inclusion Criteria1

  • university students diagnosed with moderate acne by Acne Severity Scale

Exclusion Criteria6

  • - Patients on antibiotics for other reasons in less than one month.
  • - Pregnant ladies
  • - Patients on topical anti-acne treatment
  • - Patients with liver disease
  • - Patients on topical or oral steroids
  • - Patients on oral contraceptives

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

azithromycin capsules 500 mg once daily after food for 3 days , then 500 mg once a week after food (every Friday) for total of 12 weeks. The prescription will be given in a monthly basis, each time

azithromycin capsules 500 mg once daily after food for 3 days , then 500 mg once a week after food (every Friday) for total of 12 weeks. The prescription will be given in a monthly basis, each time the students will be asked about any remaining capsules.


Locations(1)

Muscat, Oman

View Full Details on ANZCTR

For the most up-to-date information, visit the official listing.

Visit

ACTRN12619000073101