Comparison of Efficacy of Oral Azithromycin Versus Oral Doxycycline in the Treatment of Moderate Acne Vulgaris and Determination of the Effects of These Treatments on Patients' Quality of Life Among University Students.

Moderate acne is a common and often distressing skin condition, particularly among young people. Two oral antibiotics — azithromycin and doxycycline — are both used to treat acne, but there is limited direct comparison of their effectiveness in this population. This study compares the two treatments in university students over a three-month period, measuring how much each reduces acne severity and how it affects quality of life. Participants are randomly assigned to take either azithromycin or doxycycline. Their acne is assessed using a standardised severity scale at the start and every month for three months, alongside quality of life questionnaires. The goal is to identify which treatment provides better outcomes for this age group. You may be eligible if you are a university student diagnosed with moderate acne. You are not eligible if you have taken antibiotics for any reason in the past month, are pregnant, are currently using topical anti-acne treatments or topical/oral steroids, are on oral contraceptives, or have liver disease. This study is based at Sultan Qaboos University.