Optimising pain relief after knee joint replacement surgery at Counties Manukau Health; We compare two methods of local anaesthesia (numbing medicine) administration to reduce pain after knee replacement surgery.
Comparison of continuous infusion against programmed intermittent bolus of local anaesthesia through adductor canal catheter after total knee arthroplasty.
Counties Manukau Health, Middlemore Hospital Research Office
72 participants
May 1, 2019
Interventional
Conditions
Summary
We are studying how to optimise pain relief after knee joint operation. An adductor canal catheter (plastic tube placed near the nerve providing sensation to knee) is used to provide numbing medicine called local anaesthesia for pain relief after a knee joint replacement. We are looking at comparing a continuous drip of local anaesthesia versus intermittent delivery of a larger volume of local anaesthesia called a Programmed intermittent bolus (PIB). We will measure the participants satisfaction, overall use of painkillers and how well they can participate in rehabilitation. We will use the findings of this study to help us optimise our pathways for future patients having their knee replacement operation.
Eligibility
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Interventions
Patients undergoing Total Knee Arthroplasty will be randomly assigned to one of two groups in a double-blinded manner. They will all receive the established pain relief treatment (Adductor Canal Catheter - a peripheral nerve catheter) and have 0.2% ropivacaine as the local anaesthetic. 1. Group 1 - Continuous infusion of local anaesthesia at 5mls/hr of 0.2% ropivacaine (10mg/hr) 2. Group 2 - Programmed intermittent bolus of local anaesthesia - 10mls every 2 hours of 0.2% ropivacaine. (20mg every 2 hours) The infusion will start in the postoperative anaesthetic care unit (PACU) and continue for 48 hours after the start of the study drug/method of delivery. We will follow up at least once daily for 72 hours after commencing study infusion, we will check adherence to study protocol and document any violations or deviation from prescribed methods; audit of hospital records, medication charts and participant's responses will be used to monitor adherence to study protocol.
Locations(1)
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ACTRN12619000221156