Effect of adding atropine to orthokeratology on eye elongation and myopia progression in children.
The University of Auckland
32 participants
Jan 11, 2021
Interventional
Conditions
Summary
The study investigates whether there is any additional benefit of adding atropine 0.025% insertion fluid when using Orthokeratology lenses to slow the progression of myopia (short-sight) in children.
Eligibility
Inclusion Criteria3
- Between 8 to 18 years of age
- Have successfully worn Orthokeratology for more than 3 months.
- Have a spectacle prescription of -0.75D to -6.00D spherical equivalent
Exclusion Criteria4
- A difference in prescription between the two eyes greater than 1.50 Diopters
- Amblyopia, cataract or strabismus
- On medication that may interact with atropine
- A known allergy to anticholinergic drugs
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Interventions
Use of atropine (0.025%) as the lubricant fluid used when inserting overnight orthokeratology contact lenses onto the cornea of the (experimental) eye. (The fluid normally used is saline) Dose: one drop, once daily, for two years, when inserting lenses at night. Administered by parent for younger children and by participant for older children: monitored by parental diary in both cases. Cross-over between eyes at one year with no washout period (for example: right eye receives atropine for one year followed by saline for one year, whereas left eye receives saline for one year followed by atropine for one year)
Locations(1)
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ACTRN12620001046998