RoLaCaRT-1: A Randomized Trial of Robotic Surgery versus Laparoscopic Surgery for Colon Cancer

Exclusion Criteria15

• Evidence of T4 disease invading adjacent organs.
• Pre-operative surgical plan includes division of the middle colic vessels (extended right hemicolectomy) or any other more extensive colectomy procedure.
• Synchronous surgical procedure planned with right hemicolectomy.
• Urgent, unplanned or emergency surgery.
• Palliative surgical intent including non-resection, stoma formation, staging laparoscopy or open and close procedures.
• Prior formation of defunctioning ileostomy as part of treatment for this right colon cancer.
• No plan to create a surgical ileo-colonic anastomosis.
• Neoadjuvant chemotherapy administered to treat this cancer prior to resection.
• Known Crohn’s disease with active terminal ileal disease.
• History of any conditions that would preclude use of a minimally-invasive approach (e.g. multiple previous major laparotomies, severe adhesions, patient co-morbidity).
• Concurrent or previous abdominal or pelvic malignancy within five years prior to registration irrespective of treatment modality.
• Other co-morbidities or conditions that may compromise assessment of key outcomes.
• Significant metastatic disease which would be expected to impact life expectancy of at least 1 year
• Evidence of systemic disease (cardiovascular, renal, hepatic, etc.) that would preclude surgery, or other severe incapacitating disease, i.e. ASA IV (a patient with severe systemic disease that is a constant threat to life) or ASA V (a moribund patient who is not expected to survive without the operation).
• Pregnancy or lactation.