The Impact of Light and Odor on Alertness in Management of Sleep Inertia

Exclusion Criteria3

• Self reported habitual nightly sleep amounts < 6 or > 9 hours; self reported night time lights out earlier than 2100 hours during weeknights; self reported morning wake-up times
• later than 0900 during weekdays; self reported habitual napping > 1 time a week; self reported caffeine use > 400 mg (e.g. 8 caffeinated sodas or approximately 3 to 4 cups of coffee) per day, history of cardiovascular disease (including but not limited to arrhythmias, valvular heart disease, congestive heart failure, or myocardial infarction); history of neurologic disorder (including but not limited to epilepsy or another seizure disorder,
• amnesia for any reason, hydrocephalus, MS, narcolepsy or other sleep disorder); underlying pulmonary disease requiring daily inhaler use; kidney disease or abnormalities, liver disease or abnormalities; self reported history of psychiatric disorder requiring hospitalization or psychiatric product for any length of time; self reported or suspected regular nicotine use (> 1 cigarette or equivalent per week) within the last year; self reported or suspected heavy alcohol use (minimum limit to define heavy alcohol use is 14 drinks per week or as determined by the examining study licensed physician); self reported or suspected current use of other illicit drugs (including but not limited to benzodiazepines, amphetamines, cocaine, marijuana); resting blood pressure above 140/90 or resting pulse > 110; BMI > 30 (Obese Class I or greater); clinically significant values (as determined by the reviewing study physician) for any haematology or chemistry parameter; positive urine drug result during screening visit; currently taking corticosteroid or anti-inflammatory medications.