RecruitingACTRN12621001464853

Does strength training influence hamstring muscle-tendon adaptations and changes in running biomechanics?

Does chronic strength training influence hamstring muscle-tendon adaptations and changes in running biomechanics in healthy, recreationally active males?


Sponsor

Australian Catholic University

Enrollment

28 participants

Start Date

Aug 19, 2025

Study Type

Interventional

Conditions

Summary

This project will investigate how biceps femoris long head muscle and aponeurosis morphology are influenced after undertaking either a chronic concentric- or eccentric-only resistance training intervention in healthy, recreationally active males. A secondary aim is to determine the impact of these contraction mode specific interventions on biceps femoris long head muscle architecture, diffusion parameters, knee flexor strength, three-dimensional (3D) biomechanics and the musculotendinous demands experienced during running. We hypothesise this muscle-aponeurotic adaptation will be the major driving factor that influences the intrinsic tissue demands during gait (such as musculotendinous strain or fibre strain) instead of due to changes in joint kinematics or kinetics.


Eligibility

Sex: MalesMin Age: 18 YearssMax Age: 40 Yearss

Plain Language Summary

Simplified for easier understanding

Hamstring injuries are one of the most common and frustrating setbacks in running sports, often recurring despite rehabilitation. This research study examines how the hamstring muscle and its attached tendon adapt to two different types of resistance training — one focusing on concentric contractions (muscle shortening) and one on eccentric contractions (muscle lengthening under load). Understanding these adaptations could help design better injury prevention programs for athletes. Healthy, recreationally active young men complete a period of either concentric or eccentric training and then have detailed assessments of their hamstring muscle and tendon structure using MRI and ultrasound, as well as strength testing and analysis of their running biomechanics. The study focuses on the biceps femoris long head — the part of the hamstring most commonly injured in sprinting. This study is open to healthy men aged 18 to 40 who exercise at least twice per week and have no current lower limb injuries. People who have had a hamstring strain in the past three years, an ACL injury, any significant lower limb injury in the past 12 months, a pacemaker, or any non-MRI-compatible device cannot participate.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Healthy, male participants will perform 10 weeks (following randomisation) of either maximal eccentric- or concentric-only knee flexion strength training on an isokinetic dynamometer, consisting of tw

Healthy, male participants will perform 10 weeks (following randomisation) of either maximal eccentric- or concentric-only knee flexion strength training on an isokinetic dynamometer, consisting of two sessions per week for the duration of the intervention period. This will be conducted at the Movement Analysis Research Laboratory (403.B1.02A) and Exercise Science Research Lab (420.4.12) at Australian Catholic University, Melbourne. Duration of each training session will be approximately 30 mins and all sessions will be completed one-on-one with the investigator. Across the training period, the volume (number) of contractions will be increased as per the progression outlined below: Week 1: Frequency (days per week) = 2 Sets = 3 Repetitions = 6 Total repetitions = 36 Week 2: Frequency (days per week) = 2 Sets = 3 Repetitions = 6 Total repetitions = 36 Week 3: Frequency (days per week) = 2 Sets = 4 Repetitions = 6 Total repetitions = 48 Week 4: Frequency (days per week) = 2 Sets = 4 Repetitions = 6 Total repetitions = 48 Week 5: Frequency (days per week) = 2 Sets = 5 Repetitions = 6 Total repetitions = 60 Week 6: Frequency (days per week) = 2 Sets = 5 Repetitions = 6 Total repetitions = 60 Week 7: Frequency (days per week) = 2 Sets = 6 Repetitions = 6 Total repetitions = 72 Week 8: Frequency (days per week) = 2 Sets = 6 Repetitions = 6 Total repetitions = 72 Week 9: Frequency (days per week) = 2 Sets = 6 Repetitions = 8 Total repetitions = 96 Week 10: Frequency (days per week) = 2 Sets = 6 Repetitions = 8 Total repetitions = 96 All contractions will be completed at 60deg/sec on the isokinetic dynamometer. All participants will perform two sets of three warm-up efforts at 60deg/sec, in the contraction mode used for their training. For all training repetitions, the concentric training participants will be moved to full knee extension (0deg) by the investigator and will be instructed to maximally flex their knee through to 90deg of knee flexion. The lever arm will then be returned to full knee extension, and the subsequent repetition completed. This will be undertaken until all repetitions are completed in their respective set, with a 30 second rest period between sets. The eccentric training participants will begin with their knee at 90deg of flexion. They will then be instructed to maximally flex against the lever arm until full knee extension is reached (0deg). The the lever arm will then be re-positioned to 90deg of knee flexion for the subsequent contraction. This will be undertaken until all repetitions are completed in each set, with a 30 second rest period between sets. Each training session will be separated by at least 48 hours. Participants will also be asked to refrain from additional hamstring strength training during this intervention period. The participants will be paired according to biceps femoris long head aponeurosis width and randomly assigned to (allocation ratio, 1:1) either concentric- or eccentric-only knee flexor strength training group in a randomly selected limb (the contralateral limb served as a within-participant control).


Locations(1)

VIC, Australia

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