Cardiac and vascular Evaluation using 4D-flow magnetic resonance (4DCARE).
Four-dimensional flow MRI for cardiovascular evaluation (4DCARE): a prospective non-inferiority trial of a rapid cardiac MRI exam
Imaging and Phenotyping Laboratory
800 participants
Aug 1, 2017
Observational
Conditions
Summary
To perform a prospective non-inferiority study of a rapid cardiac MRI acquisition protocol using 4D-flow compared to the current gold standard cardiac MRI examination to measure cardiac function and detect pathology
Eligibility
Inclusion Criteria1
- Adults with an indication for cardiac MRI
Exclusion Criteria3
- Thoracic metallic implant (including pacemaker, cardiac defibrillation device)
- Inability to tolerate exam
- Other contraindication to MRI (including contraindication to IV contrast)
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Interventions
Patients referred by their doctor for Cardiovascular magnetic resonance imaging are invited to participate in the study. Participants undergo a single imaging session including both the compressed 4D-flow protocol (4DCARE-CP), and the complete conventional Cardiovascular magnetic resonance imaging protocol (CMR-FP). The study exam time is equal to the standard length of a typical cardiac MRI exam as the 20 minute 4D-flow protocol is nested within a total 45 min exam time.
Locations(4)
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ACTRN12622000047796