ClinicalTrialsFinder
TerminatedPhase 4ACTRN12622000686707

Comparison of the analgesic effect of acetaminophen, morphine and lidocaine for postoperative pain following cardiac surgery

Comparison of the analgesic effect of acetaminophen, morphine and lidocaine for postoperative pain following cardiopulmonary bypass grafting

Sponsor

University Clinical Center of Kosovo

Enrollment

90 participants

Start Date

Nov 25, 2019

Study Type

Interventional

Conditions

Pain after cardiopulmonary bypass graft

Summary

The primary purpose of this study is to compare the analgesic effect of lidocaine in reducing intensity of pain in patient undergoing cardiac surgery, for coronary artery bypass graft . The comparison was done with two other analgesics, acetaminophen and morphine , as a control treatment for reducing intensity of pain in patient undergoing cardiac surgery, for coronary artery bypass graft . Intravenous administration of lidocaine provides a more satisfactory postoperative analgesia compared to the application of morphine and acetaminophen in the postoperative period

Eligibility

Sex: Both males and femalesMin Age: 18 YearssMax Age: 75 Yearss

Inclusion Criteria2

  • All the patient planed for elective cardiopulmonary bypass surgery,
  • ASA classification (American Society of Anesthesiologists ) II-IV

Exclusion Criteria6

  • patient rejection,
  • unconscious patients,
  • patients taking chronically opioids
  • patient with renal insufficiency gr III-IV, hepatic insufficiency gr III-IV,
  • psychiatric patients,
  • patients allergy in acetaminophen, morphine or lidocaine respectively

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

Post operative pain management after cardiac surgery. The goal of the intervention is to reduce the intensity of pain. Two groups are included in the study as control treatment, each group has 20 p

Post operative pain management after cardiac surgery. The goal of the intervention is to reduce the intensity of pain. Two groups are included in the study as control treatment, each group has 20 patients Group 1(A) has received acetaminophen intravenous 1gr every 4 hour, for 48 hours post operative, starting immediately upon termination of anesthesia Group 2 (M) received morphine intravenous 5mg every 6 hours, for 48 hours post operative, starting immediately upon termination of anesthesia

Locations(1)

Kosovo, Albania

View Full Details on ANZCTR

For the most up-to-date information, visit the official listing.

Visit

ACTRN12622000686707