RecruitingPhase 1ACTRN12624000276550

Topical use of Eucalypt sap resin for damaged skin

Safety and efficacy of Eucalypt sap resin for inflammatory skin conditions and wound care in adults – An exploratory case series


Sponsor

Integria Healthcare (Australia) Pty Ltd.

Enrollment

60 participants

Start Date

Apr 24, 2024

Study Type

Interventional

Conditions

Summary

This protocol aims to explore the potential effectiveness of topical eucalypt sap resin application across a range of both acute and chronic skin injury and inflammatory conditions, using this novel Australian native ingredient with antimicrobial, styptic, and astringent properties. Skin conditions to be evaluated as individual case studies under this protocol cover wound care (both acute and chronic), fungal skin infections, acne, insect bites and sunburn.


Eligibility

Sex: Both males and femalesMin Age: 18 YearssMax Age: 70 Yearss

Plain Language Summary

Simplified for easier understanding

Eucalyptus trees produce a sticky sap resin that has been used in traditional settings for its antimicrobial and wound-healing properties. This study by Integria Healthcare is taking a closer look at whether this natural ingredient, applied directly to the skin, can genuinely help with a range of common skin conditions. The study will explore its use as individual case studies for people with wounds (both new and chronic), fungal skin infections, acne, insect bites, and sunburn. Each participant will have the eucalypt sap resin applied topically to their affected area, and the team will track how the condition responds over time. You may be eligible if you are an adult aged 18-70 with an inflammatory skin condition or wound. People who are pregnant or breastfeeding, or who have used topical or oral antibiotics, antifungals, or steroids in the past 3 days are not eligible. This is an early-stage exploratory study that aims to build the evidence base for this uniquely Australian natural ingredient.

This is a simplified summary. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Arm A - Eucalypt extract (C5-2024) in inert gel formulation The treatment will be individualised as appropriate for each case and documented as individual case studies. The gel will be applied topi

Arm A - Eucalypt extract (C5-2024) in inert gel formulation The treatment will be individualised as appropriate for each case and documented as individual case studies. The gel will be applied topically to affected skin area at a dose of 1mL per cm2. For all wound presentations, the product will be applied by a wound care nurse in a medical clinic, in accordance with standard wound management guidelines appropriate for the type of wound, i.e. application and re-dressing every 7 days or as required. For all other conditions, the product will be applied by the participant themselves in their home environment. Adherence and overall usage of test product will be checked by monitoring of remaining gel amounts.


Locations(1)

NSW,QLD, Australia

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ACTRN12624000276550