Effects of antibiotic prophylaxis in dental implant surgery for adult patients: Randomized controlled clinical trial.
Effects of antibiotic prophylaxis on rates of early implant failure in dental implant surgery for adult patients: Randomized controlled clinical trial.
Master in Oral Surgery and Implantology, University of Granada
100 participants
Oct 1, 2024
Interventional
Conditions
Summary
Our objective is to evaluate the effect of a single dose of 2 g of oral amoxicillin administered 1 h before placement of single or multiple implants placed in a single surgical field in healthy adults versus placebo to reduce early failure of implants and postoperative infectious complications. The main hypothesis of this study is that there are no differences in the incidence of early implant failures and infectious complications after implant surgery oral implants in healthy, periodontally treated adults by administering a dose single dose of 2 grams of oral amoxicillin 1 hour before the intervention versus placebo.
Eligibility
Inclusion Criteria5
- Patients 18 years and over
- Subjects treated periodontally, if necessary, prior to placement
- of implants
- Presence of sufficient bone and soft tissue that does not imply augmentation surgery in the moment of implant placement
- Implants placed in a single surgical field
Exclusion Criteria12
- Patients who, due to their medical condition, require antibiotic prophylaxis
- postoperative (risk of endocarditis)
- Patients undergoing head and neck radiotherapy less than 2 years ago
- Diabetics (controlled and uncontrolled)
- Allergic to penicillin
- Patients treated with antiresorptive drugs
- Pregnant or breastfeeding
- Immunocompromised
- Patients who are taking antibiotics for other reasons
- Implants that require simultaneous bone regeneration
- Implants in which immediate loading is carried out
- Immediate implants
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Interventions
Our objective is to evaluate the effect of a single dose of 2 g of oral amoxicillin administered 1h before placement of single or multiple implants placed in a single surgical field in healthy adults versus placebo. Patient adherence is controlled by direct observation.
Locations(1)
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ACTRN12624001151527