CompletedPhase 2Phase 3ACTRN12624001209583

Comparative Study of Hyperbaric Bupivacaine plus Ketamine vs. Bupivacaine plus Fentanyl for Spinal Anesthesia during Cesarean Section.

Comparative Study of Hyperbaric Bupivacaine plus Ketamine vs. Bupivacaine plus Fentanyl for Spinal Anesthesia during Cesarean Section. A prospective , Randomized , Double -Blind, controlled study in pregnant women with age (18-45) years old.


Sponsor

Mohammed Joori

Enrollment

105 participants

Start Date

Jun 7, 2020

Study Type

Interventional

Conditions

Summary

this study was administered Preservative-free ketamine 15 mg plus bupivacaine 10 mg (Marcaine) 0.5%, and in the B group bupivacaine 10 mg (Marcaine) 0.5% alone, Our hypothesis is that there are a significant relationship between the duration of analgesia, length of sensory and motor blockade between ketamine, fentanyl, and bupivacaine groups intraoperative and post-operative.


Eligibility

Sex: FemalesMin Age: 18 YearssMax Age: 45 Yearss

Inclusion Criteria1

  • A pregnant women with age (18-45) years old and planned for elective cesarean sections delivery with ASA Classification I &II, at specialized Arab hospital.

Exclusion Criteria1

  • Pregnant women with spinal block contraindications and those with a history of ketamine medication allergies.

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Interventions

Interventional group was administered Preservative-free ketamine 15 mg plus bupivacaine 10 mg (Marcaine) 0.5%, and in the B group was administered bupivacaine 10 mg (Marcaine) 0.5% alone

Interventional group was administered Preservative-free ketamine 15 mg plus bupivacaine 10 mg (Marcaine) 0.5%, and in the B group was administered bupivacaine 10 mg (Marcaine) 0.5% alone. The strategies we’re used to evaluate the patient through self monitoring and closed observation. An anesthesiologist performed the spinal puncture by pencil-point spinal needle (27 Fr) between the L3 to L4 or L4–L5 vertebrae with the patient in a sitting position on the side of the operation table.


Locations(1)

Nablus, Palestinian Territory, Occupied

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ACTRN12624001209583