Lactation Intensity and reduction in the prevalence of metabolic syndrome after a maternal complication of pregnancy: an observational cohort analysis
Lactation Intensity and reduction in the prevalence of metabolic syndrome after a maternal complication of pregnancy: an observational cohort analysis in women with a previous pregnancy complication.
University of Adelaide
250 participants
Sep 1, 2023
Observational
Conditions
Summary
Major pregnancy complications such as preeclampsia and gestational diabetes mellitus are associated with development of type II diabetes mellitus and coronary heart disease, which are becoming ever more prevalent in young women. Despite clinical recommendations to optimise cardiovascular disease (CVD) risk factors after a complication of pregnancy, tailored lifestyle programs have poor adherence and are not suited to the lifestyle of a mother during the early postpartum period. Breastfeeding (lactation) is associated with a reduction in hypertension and diabetes later in life, however there has not been a direct focus on elucidating how breastfeeding affects certain components of cardiometabolic health in women with a previous pregnancy complication within the early postpartum period. We hypothesize that those who have a higher lactation intensity over 6 months postpartum (>=0.8 intensity score) will have a lower risk of metabolic syndrome at 6 months postpartum following a major pregnancy complication. This project aims to determine if lactation intensity is associated with a reduction in the rate of metabolic syndrome at 6 months postpartum in women with a maternal complication of pregnancy.
Eligibility
Inclusion Criteria6
- Women with a previous pregnancy complication who are referred to a postpartum cardiovascular preventative clinic at 6 months postpartum:
- Hypertensive disorders of pregnancy (including gestational hypertension, preeclampsia, eeclampsia and HELLP syndrome), requiring medical therapy or resulting in <37 weeks’ gestation;
- Gestational diabetes mellitus requiring metformin or insulin therapy;
- Preterm delivery at <35 weeks’ gestation;
- Delivery of a small for gestational age infant;
- Placental abruption
Exclusion Criteria2
- Patients without ability to provide informed consent
- Patients <18 years of age
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Interventions
Eligible women who are referred to COFFEE (Cardiovascular Assessment After Obstetric Complications: Follow-Up For Education and Evaluation) clinic are included in this study. COFFEE clinic is a postpartum cardiovascular preventative service at the Lyell McEwin Hospital for women with previous complications of pregnancy. They are routinely assessed by a cardiac nurse practitioner at 6 months, 18 months and 5 years post-pregnancy for cardiovascular disease risk and primary prevention through lifestyle modification. Women at the time of their antenatal discharge will be contacted by the researcher either at time of discharge or within 5 weeks of discharge via telephone to participate in the study. Upon informed consent and enrollment to the study, participants will be asked to complete short, online questionnaires once a month on breastfeeding difficulties, and infant feeding patterns. They will complete 1 questionnaire a month for the period of 6 months. Data from their COFFEE clinic postpartum appointment at 6 months will be collected to assess cardio-metabolic risk factors including weight, blood pressure and biochemical markers.
Locations(1)
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ACTRN12624001351505