RecruitingACTRN12624001361594

Children and Adolescents: Respiratory Infection and Long-term Effects (CARE Study)

A longitudinal study of post-viral sequelae following common respiratory infections in children and adolescents


Sponsor

Women's and Children's Hospital Network

Enrollment

4,000 participants

Start Date

Jun 20, 2024

Study Type

Observational

Conditions

Summary

This study investigates ongoing symptoms following COVID-19 and influenza infections in children and teenagers. Parents of children who have had COVID-19 or influenza will be invited to participate. Initially, cases will be identified through presentations at the Women's and Children's Hospital and will then expand to include statewide notifications. After providing consent, participants (or their parents) will complete surveys at the start of the study and then again at 3, 6, and 12 months after the viral infection. These surveys will help researchers monitor any persistent health issues over time. The primary goal of the study is to understand how common these ongoing health problems are in young people and how they impact their daily lives.


Eligibility

Sex: Both males and femalesMin Age: 0 YearssMax Age: 17 Yearss

Plain Language Summary

Simplified for easier understanding

Since the COVID-19 pandemic, there has been growing awareness that some children and teenagers experience ongoing symptoms long after their initial infection clears — sometimes called 'long COVID.' Similar patterns have been observed after influenza. Understanding how common this is in young people, and how it affects their school attendance, activities, and wellbeing, is an important public health priority. The CARE Study is following children and teenagers aged 0 to 17 in South Australia who have tested positive for COVID-19 or influenza. Parents or children (depending on age) complete surveys at the start of the study and again at 3, 6, and 12 months after the infection, to track any health symptoms that persist over time. Your child may be eligible if they have tested positive for SARS-CoV-2 or influenza (by PCR or rapid antigen test) within the past 2 months and are under 18 years old. The study is survey-based and can be completed from home. A parent or guardian must be able to provide consent. Children receiving palliative care are not eligible.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Children and adolescents aged 0 to 17 who have tested positive for COVID-19 or influenza are eligible for enrollment. Those who consent will be asked to complete a baseline, 3-month, 6-month, and 12-m

Children and adolescents aged 0 to 17 who have tested positive for COVID-19 or influenza are eligible for enrollment. Those who consent will be asked to complete a baseline, 3-month, 6-month, and 12-month online survey. Each online survey takes approximately 10 minutes. Participants are enrolled in the study for 12 months.


Locations(1)

SA, Australia

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