A study testing a gel containing 0.1% mometasone furoate, applied once a day, to see if it helps in the treatment of chronic leg wounds

Chronic leg wounds — wounds that have not healed within a month despite standard treatment — are a common and difficult problem, particularly in older adults. They can cause significant pain, limit mobility, and reduce quality of life. Inflammation is a key barrier to wound healing, and corticosteroid medications (which reduce inflammation) have been used to treat some skin conditions, but their use in wound healing has not been well studied. This study is testing a topical hydrogel containing a low dose of mometasone furoate (a mild corticosteroid) applied once daily to chronic lower leg wounds over 28 days. Participants are randomly assigned to either the active gel or a placebo gel and assessed over 5 weeks for wound size reduction, inflammatory markers, and adverse effects. You may be eligible if you are 18 or older, have a chronic lower leg wound that has not healed for at least one month despite conventional treatment, and are not taking other topical or systemic treatments that could interfere with results. People with pregnancy, diabetes, chronic kidney or liver disease, or known allergies to the product's ingredients are not eligible.