The A1 Protein Free Vs Conventional milk study in lactose tolerant and lactose intolerant consumers
A randomised, controlled, double-blind, crossover pilot study investigating the metabolism of lactose following consumption of A1 and A2 beta casein milk proteins in lactose tolerant and lactose intolerant consumers
The a2 Milk Company
50 participants
Jul 11, 2025
Interventional
Conditions
Summary
Conventional milk generally contains A1-type beta casein proteins which have been found to cause symptoms of lactose intolerance in some people. We want to see if symptoms of lactose intolerance are less when people drink A1 protein free milk, when compared to drinking conventional milk containing A1 protein. We also want to confirm this with physiological markers in blood, urine, and faeces, and measure them over time.
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
A single oral dose (300mL) of A1 Protein Free milk taken under fasted conditions (only water for 10 hours) at the MRINZ clinical room following a 7 day washout of dairy products. The dosing is to be witnessed by an investigator, the whole dose must consumed in under 5 minutes. There is a 7 day washout between crossover doses.
Locations(1)
View Full Details on ANZCTR
For the most up-to-date information, visit the official listing.
ACTRN12625000285459