RecruitingACTRN12625001008415

Effectiveness of hysteroscopic resection of a niche VERSUS Expectant management in women with premenstrual spotting postmenstrual spotting

Effectiveness of hysteroscopic resection of a niche VERSUS Expectant management in women with premenstrual spotting , A randomized controlled trial. .


Sponsor

Maternity and children hospital faculty of medicine Minia University

Enrollment

110 participants

Start Date

Sep 28, 2025

Study Type

Interventional

Conditions

Summary

efficacy of hystroscpic resection of cesarean section niche for management purpose to improve post menstrual spotting .


Eligibility

Sex: FemalesMin Age: 18 YearssMax Age: 45 Yearss

Inclusion Criteria5

  • Women aged 18–45 years.
  • History of at least one cesarean delivery.
  • Presence of a uterine niche on transvaginal ultrasound.
  • Complaints of postmenstrual spotting lasting >2 days per cycle.
  • Regular menstrual cycles

Exclusion Criteria4

  • Active pelvic infection
  • known coagulation disorders.
  • Intrauterine device in place.
  • Other causes of abnormal uterine bleeding (e.g., fibroids, polyps

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

General or regional (spinal) anesthesia depending on the extent of the procedure and surgeon preference. duration of the intervention : 30 -60 minutes . surgeon : senior specialist of endoscopic su

General or regional (spinal) anesthesia depending on the extent of the procedure and surgeon preference. duration of the intervention : 30 -60 minutes . surgeon : senior specialist of endoscopic surgery. *Positioning: Lithotomy position with appropriate padding to avoid nerve injury. Bladder should be emptied before the procedure. 3. Surgical Equipment: *Rigid hysteroscope (5–9 mm) with operative channel. *30° lens for better visualization. *Electrosurgical loop momopolar or bipolar resectoscope . *Uterine distension medium (normal saline for bipolar or glycine for monopolar energy). *Cervical dilators, if necessary. *Fluid management system to monitor inflow and outflow.Cervical Dilation (if required): Gradual dilation up to size compatible with the resectoscope. 2. Diagnostic Hysteroscopy: Initial inspection of uterine cavity to locate the cesarean scar defect, usually found at the anterior lower uterine segment. 4. Identification of Niche: Appears as a pouch or depression at the scar site, often with retained blood or mucus. 5. Resection Steps: a. Resect the Inferior Edge: Use a bipolar loop or scissors to excise the fibrotic and overhanging inferior edge of the niche to improve drainage and eliminate the pocket. *Remove any granulation tissue or polypoidal growth inside the niche. *Avoid aggressive resection of the superior edge to minimize thinning of the overlying myometrium. c. Coagulation: Apply light coagulation to bleeding points, avoiding excessive energy near the uterine serosa. 6.Fluid Balance Monitoring: Monitor input and output of distension fluid to avoid fluid overload (especially with glycine). strategies to assess the adherence to the intervention is accurate record of operative notes.


Locations(1)

Egypt

View Full Details on ANZCTR

For the most up-to-date information, visit the official listing.

Visit

ACTRN12625001008415