The effect of clove oil as a topical analgesic during tooth restoration
A randomized controlled trial to evaluate the analgesic effect of clove oil applied topically during restorative tooth preparation in patients with occlusal caries
Ayesha Noor; Khyber College of Dentistry
132 participants
Nov 1, 2025
Interventional
Conditions
Summary
This study will test whether clove oil can help reduce pain during tooth filling procedures. Adult patients with dental cavities will be randomly given either clove oil or a placebo oil before treatment. Their pain will be measured using a simple pain scale. The goal is to see if clove oil provides effective pain relief without the side effects of common pain medicines. This research hopes to make dental treatment more comfortable using a natural option.
Eligibility
Inclusion Criteria3
- Adults aged 18–50 years
- Presence of occlusal caries up to D2 level in posterior teeth
- No clinical or radiographic evidence of periapical pathology
Exclusion Criteria4
- Pregnant or lactating women
- Patients with systemic conditions affecting neural sensitivity or dental health (e.g., diabetes)
- Use of desensitizing products or analgesics/NSAIDs within 24 hours
- History of hypersensitivity to clove oil
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Interventions
Name: Clove oil Description: Clove oil will be applied topically using a cotton pellet twice for 60 seconds, 10 minutes prior to restorative tooth preparation. Mode of delivery: Topical application on the tooth Duration: Single application prior to the procedure Dose: Two 60-second applications The researcher will administer clove oil by herself and will assess the adherence to intervention by direct observation
Locations(1)
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ACTRN12625001207404