RecruitingPhase 2Phase 3ACTRN12625001306404

Comparing the therapeutic efficacy of oral minoxidil and oral finasteride in androgenic alopecia in males

Sponsor

Pakistan naval ship Shifa hospital, Karachi

Enrollment

62 participants

Start Date

Nov 3, 2025

Study Type

Interventional

Conditions

Androgenic alopecia

Summary

A comparative study of oral minoxidil 1.25 mg daily with oral finasteride 1 mg on alternate days in androgenic alopecia, will be conducted at Dermatology out-patient department, PNS Shifa hospital Karachi after fulfilling the inclusion and exclusion criteria. After the informed written consent and permission from hospital’s ethics review committee, 62 patients will be divided in Group A & B. Patients in both the groups will receive treatment for 6 months and data from patient will be collected through a proforma on first visit and follow-ups', etc. The study aims to compare the effectiveness of two medications, oral minoxidil and oral finasteride, in treating androgenic alopecia (male pattern baldness).

Eligibility

Sex: MalesMin Age: 18 YearssMax Age: 45 Yearss

Inclusion Criteria5

Male
Age 18-45 years
Androgenetic alopecia with Hamilton-Norwood scale - Stage I - IV
Patients without any known systemic illness / psychiatric illness
Patients not taking any treatment for last 3 months

Exclusion Criteria5

Patients on any systemic / immuno-suppressive therapy
Cases with any hepatic or renal failure
Patients who are known to be hypersensitive to minoxidil or finasteride
Patients using other therapies for restoring hair or taking any other systemic medications (like steroids, cytotoxic drugs or others)
Patients with androgenic alopecia associated with other dermatological conditions.

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Interventions

Patients will be randomized into two groups (Group A&B). Group A will receive oral minoxidil 1.25mg daily ( Tab Minoxidil 2.5mg will be split into 2 halves and each half will be taken daily). All the

Patients will be randomized into two groups (Group A&B). Group A will receive oral minoxidil 1.25mg daily ( Tab Minoxidil 2.5mg will be split into 2 halves and each half will be taken daily). All the patients will be provided with the same brand of medicine to minimize brand bias. All patients will asked to bring used tablet pack at every visit ( 1 visit per month) for adherence purposes.