The Effectiveness of Retrolaminar and Modified Thoracolumbar Interfascial Plane Blocks in the Management of Opioid-Free Anesthesia in Lumbar Discectomy
Comparison of the Effects of Retrolaminar and Modified Thoracolumbar Interfascial Plane Blocks on Postoperative Pain and Recovery Under Opioid-Free Anesthesia Management in Patients Undergoing Lumbar Discectomy: A Prospective, Double-Blind Study
Onur KUCUK (Dokuz Eylül University)
70 participants
Nov 20, 2025
Interventional
Conditions
Summary
This randomized, controlled, prospective study aims to compare the effects of Retrolaminar Block and Modified Thoracolumbar Interfascial Plane (mTLIP) Block on postoperative recovery parameters in patients undergoing lumbar discectomy under opioid-free general anesthesia.All participants will receive standardized general anesthesia without intraoperative opioid use. Preoperative pain sensitivity will be assessed using the Pain Sensitivity Questionnaire (PSQ) and Visual Analog Scale (VAS). The study's primary outcomes include the time from sevoflurane discontinuation to the first response to verbal command and the time to discharge from the post-anesthesia care unit (PACU), defined as reaching an Aldrete score greater than or equal to 9. Secondary outcomes include tracheal extubation time, postoperative VAS scores at specified intervals (30 min, 2 h, 4 h, 8 h, 12 h, and 24 h), time to first rescue analgesic request, total 24-hour analgesic consumption, and the incidence of postoperative nausea and vomiting.
Eligibility
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Interventions
Group Retrolaminar Block (RLB): Participants in this group will receive an ultrasound-guided bilateral Retrolaminar Block (RLB) prior to the induction of general anaesthesia. The procedure involves the injection of 18 mL %0.25 bupivakain, 2 mL (8 mg) deksametazon on each side into the retrolaminar space at the L3 vertebral level using an in-plane technique. The injection is performed under sterile conditions using a linear ultrasound probe to visualize the lamina and ensure correct needle placement. - Drug: 18 mL %0.25 bupivakain, 2 mL (8 mg) deksametazon; 20 mL per side - Mode of administration: Single-shot injection, ultrasound-guided - Timing: Applied once after general anesthesia induction and intubation. - Monitoring adherence: Procedure details and drug dosage are recorded in patient medical records and anaesthesia charts.
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ACTRN12625001437459