Von Hippel-Lindau (VHL): Clinical Manifestations, Diagnosis, Management and Molecular Bases of Inherited Renal and Other Urologic Malignant Disorders

This study examines people with inherited kidney and urinary tract cancers — including Von Hippel-Lindau (VHL) syndrome — to understand the genetic causes and improve how these conditions are managed. **You may be eligible if...** - You are 2 years of age or older - You have a diagnosed or suspected inherited urologic cancer (such as VHL, hereditary papillary renal carcinoma, Birt-Hogg-Dubé, or related syndromes) - You are a biological family member of someone with one of these conditions - You have features such as kidney tumors, certain brain or spinal growths, eye abnormalities, or adrenal gland tumors that suggest a hereditary condition **You may NOT be eligible if...** - There are no formal exclusion criteria — anyone meeting the inclusion criteria may be considered Talk to your doctor to see if this trial is right for you.