RecruitingNCT00198068

Predictors of Pregnancy Outcome in Systemic Lupus Erythematosus (SLE) and Antiphospholipid Syndrome (APS)


Sponsor

Hospital for Special Surgery, New York

Enrollment

700 participants

Start Date

Sep 1, 2003

Study Type

OBSERVATIONAL

Conditions

Summary

The PROMISSE Study is an observational study of 700 pregnant patients, enrolled at nine major clinical centers. The purpose of the study is 1) to determine whether certain proteins (called complement split products) that can injure healthy organs can be used to predict poor pregnancy outcome in patients with systemic lupus erythematosus (SLE) and anti-phospholipid syndrome (APS), and/or 2) to determine whether elevated levels of circulating antiangiogenic factors predict pregnancy complications in patients with aPL antibodies and/or SLE.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 45 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a new treatment for people with antiphospholipid syndrome and systemic lupus erythematosus. The study is currently recruiting participants at 10 locations. People eligible for this study include women aged 18 Years to 45 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(10)

Northwestern University

Chicago, Illinois, United States

University of Chicago

Chicago, Illinois, United States

Johns Hopkins Hospital

Baltimore, Maryland, United States

NYU Langone Medical Center/Hospital for Joint Diseases

New York, New York, United States

Hospital for Special Surgery

New York, New York, United States

Columbia University Medical Center

New York, New York, United States

Oklahoma Medical Research Foundation

Oklahoma City, Oklahoma, United States

University of Utah Salt Lake City

Salt Lake City, Utah, United States

Mt. Sinai Hospital

Toronto, Ontario, Canada

Guy's & St Thomas' NHS Foundation Trust

London, United Kingdom

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NCT00198068


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