RecruitingNCT00291096

High Risk Breast Clinic: Protocol for Women at Increased Risk for Developing Breast Cancer

Sponsor

Carol Fabian, MD

Enrollment

3,000 participants

Start Date

Aug 1, 1989

Study Type

OBSERVATIONAL

Conditions

Breast Cancer

Summary

The overall goal of this project is to develop an integrative system of breast cancer risk assessment based on epidemiologic and biologic risk variables, as well as to develop or refine risk biomarkers which may be useful in predicting and monitoring response to prevention interventions.

Eligibility

Sex: FEMALEMin Age: 30 YearsMax Age: 65 Years

Inclusion Criteria7

women with at least 2 times the normal risk of developing breast cancer
between the ages of 30-65 (or within 10 years of youngest age at diagnosis in first degree relative)
greater than six months from ingestion of antihormonal therapy
greater than 1 year from pregnancy, lactation, or chemotherapy
willing to have a mammogram within six months prior to RPFNA
willing to discontinue NSAIDS or herbal supplements
willing to have blood drawn

Exclusion Criteria4

no metastatic malignancy of any kind
no breast implants or tram flap reconstructions
no radiation to both breasts
no women who have a current mammogram or clinical breast exam suspicious for cancer