RecruitingNCT00330447

Effects of Oncological Treatment During Pregnancy on Mother and Child

Oncological Treatment During Pregnancy: Pharmacokinetics of Chemotherapy and Long Term Follow up of the Offspring

Sponsor

University Hospital, Gasthuisberg

Enrollment

5,000 participants

Start Date

Aug 1, 2005

Study Type

OBSERVATIONAL

Conditions

Cancer Pregnancy

Summary

The researchers aim to investigate the outcome (overall survival) of mothers who are diagnosed and/or treated for cancer during pregnancy. Furthermore they want to test the hypothesis that children who were exposed to cancer or cancer treatment (cytotoxic drugs, radiation therapy, targeted therapy,...) develop normally (neurologic and cardiologic examination).

Eligibility

Sex: FEMALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study follows mothers who received cancer treatment during pregnancy and their children, tracking the long-term health effects on both the mother and the baby. **You may be eligible if...** - You were diagnosed with cancer during pregnancy and received treatment (chemotherapy, radiation, or surgery) while pregnant - Your child was exposed to cancer treatment before birth - You and your child are willing to attend follow-up assessments **You may NOT be eligible if...** - You are unwilling or unable to provide informed consent - You or your child cannot attend follow-up visits - Your situation does not meet the specific study criteria for type of cancer or treatment received Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(33)

Cooper University Hospital (2015-ongoing)

Camden, New Jersey, United States

Instituto Alexander Fleming

Buenos Aires, Argentina

Universitätsklinik für Frauenheilkunde und Geburtshilfe (retrospective 2016-2018)

Graz, Austria

UCL Brussels (2013-ongoing)

Brussels, Belgium

UZ Gasthuisberg, Katholieke Universiteit Leuven (2004-ongoing)

Leuven, Belgium

University Hospital Ostrava (2018-ongoing)

Ostrava, Czechia

3rd medical faculty of Charles University (2010-ongoing)

Prague, Czechia

Copenhagen University Hospital (2015-ongoing)

Copenhagen, Denmark

Hopital Bichat-Claude-Bernard (retrospective until 2018)

Paris, France

Universitätsklinik Freiburg (retrospective until 2018)

Freiburg im Breisgau, Germany

Euroclinic Hospital (2016-ongoing)

Athens, Greece

Hellenic Anticancer-Oncological Hospital of Athens (retrospective 2015-2018)

Athens, Greece

Ioannina University Hospital (retrosepctive 2015-2018)

Ioannina, Greece

Hippokration Hospital (retrospective 2015-2018)

Thessaloniki, Greece

European Institute of Oncology (2010-ongoing)

Milan, Italy

Fondazione IRCCS Ca'Granda Ospedale Maggiore (2012-ongoing)

Milan, Italy

Fondazione IRCCS Ca'Granda Ospedale Maggiore Policlinico Milano (2017-ongoing)

Milan, Italy

San Raffaele Hospital (2017-ongoing)

Milan, Italy

CIttà della Salute e della Scienza di Torino (2015-ongoing)

Torino, Italy

Regional Hospital of High Specialty of Ixtapaluca (2018-ongoing)

Ixtapaluca, Mexico

Erasmus Medical Center (2014-ongoing)

Rotterdam, Netherlands

Haukeland University Hospital (2017-ongoing)

Bergen, Norway

Medyczne Macierzynstwo (retrospective 2010-2018)

Krakow, Poland

University Hospital Krakow (2018-ongoing)

Krakow, Poland

Pozanan University of Medical Sciences (2017-ongoing)

Poznan, Poland

Hospital de Vila Franca de Xira (2017-ongoing)

Vila Franca de Xira, Portugal

N.N.Blokchin National Medical Research Center of Oncology (2013-2018 retrospective; 2018-ongoing prospective)

Moscow, Russia

Research Center for Obstetrics, Gynecology and Perinatology (2014-ongoing)

Moscow, Russia

Almazov National Medical Research Center (2018-ongoing)

Saint Petersburg, Russia

Karolinska University Hospital (2017-ongoing)

Stockholm, Sweden

F.Hached University Teaching Hospital (retrospective 2016-2018)

Sousse, Tunisia

Trakya University Faculty of Medicine (retrospective 2015-2018)

Edirne, Turkey (Türkiye)

Grigoriev Institute for medical Radiology (retrospective until 2018)

Kharkiv, Ukraine

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